OA02.03
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Progress toward HIV elimination goals: trends in and projections of treatment as prevention strategy in 38 African countries

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BACKGROUND: We aimed to estimate the trends and projections of indicators of Treatment-as-Prevention (TasP), the key global strategy for HIV elimination in Africa, and to calculate the probability of reaching key UNAIDS targets.
METHODS: We included 1,456,224 sexually active adults age 15-49 in 38 African countries from 112 nationally representative population-based surveys 2003-2018. Bayesian mixed-effect models were applied to estimate the prevalence of annual HIV testing and condom use for every country and year to 2030, and the probability of reaching UNAIDS targets in 2020 and 2030.
RESULTS: Most countries have upward trends in TasP outcomes, but seven saw downward trends in annual HIV testing and five saw decreases in condom use (Figure1). The highest coverage of annual HIV testing in 2030 is predicted in Swaziland with 92.6% (95%CrI: 74.5%-98.1%), Uganda with 90.5% (72.2%-97.2%) and Lesotho with 90.5% (69.4%-97.6%). Meanwhile, Swaziland, Lesotho, and Namibia will have the highest proportion of condom use in 2030 at 85.0% (57.8%-96.1%), 75.6% (42.3%-93.6%), and 75.5% (42.4%-93.2%). The probabilities of reaching targets range from 0% to 28.5% for HIV testing and 0% to 12.1% for condom use and no country showed a high probability (>50%) of meeting either target (Table1).

Table 1: Estimated coverage and annual rate of change (ARC) of annual HIV testing and condom use in 38 African countries, 2003'2030
CountryAnnually tested for HIV
(95% Credible Interval)
Condom used at last sex
(95% Credible Interval)

2003201020202030ARC
(%)
% reaching targets*2003201020202030ARC
(%)
% reaching targets*
Angola49.0
(31.2, 67.8)
61.1
(42.2, 77.1)
76.0
(53.3, 89.5)
86.5
(61.9, 96.2)
4.3
(-0.4, 9.6)
6.0%9.6
(4.1, 20.8)
11.6
(5.7, 22.4)
14.9
(6.8, 29.6)
18.9
(6.8, 42.3)
-0.0
(-4.6, 4.9)
0.0%
Benin44.1
(27.6, 61.6)
43.2
(27.5, 60.6)
42.2
(24.2, 62.7)
41.1
(19.2, 67.0)
-3.2
(-6.8, 0.4)
0.0%7.4
(3.7, 14.1)
8.2
(4.4, 14.7)
9.5
(4.8, 18.1)
11.0
(4.5, 24.7)
-1.3
(-5.3, 2.6)
0.0%
Burkina Faso45.2
(28.4, 62.7)
48.3
(28.9, 68.1)
52.8
(24.6, 79.1)
57.1
(18.5, 88.9)
-1.0
(-6.9, 5.2)
0.3%11.6
(5.9, 21.2)
13.7
(6.9, 25.2)
17.4
(6.9, 36.9)
21.7
(5.8, 54.2)
-0.1
(-5.5, 4.9)
0.0%
Burundi46.2
(29.4, 63.9)
49.8
(32.3, 67.6)
55.0
(33.4, 75.1)
60.4
(31.6, 83.3)
-0.7
(-4.7, 3.4)
0.0%5.1
(2.2, 10.9)
5.1
(2.5, 9.8)
5.1
(2.3, 10.7)
5.1
(1.7, 14.2)
-2.8
(-7.7, 1.7)
0.0%
Cameroon45.5
(28.8, 63.3)
46.5
(29.6, 64.2)
47.8
(25.8, 70.8)
49.3
(20.3, 78.1)
-2.2
(-6.7, 2.3)
0.0%17.5
(9.4, 30.5)
22.5
(12.8, 36.3)
31.1
(16.4, 51.4)
41.3
(18.0, 70.1)
1.6
(-3.0, 6.5)
0.0%
Central Africa45.4
(28.0, 63.6)
48.7
(29.3, 68.7)
53.3
(24.3, 80.3)
57.9
(18.0, 89.9)
-0.9
(-6.9, 5.5)
0.3%8.2
(3.8, 16.8)
9.5
(4.4, 19.0)
11.6
(4.3, 27.4)
14.0
(3.5, 41.5)
-0.6
(-6.0, 5.0)
0.0%
Chad47.4
(30.4, 65.1)
54.0
(35.6, 70.9)
63.6
(40.3, 81.9)
71.9
(40.7, 90.6)
1.1
(-3.3, 5.7)
0.2%4.2
(2.0, 8.2)
3.8
(2.0, 7.3)
3.4
(1.4, 7.8)
3.0
(0.9, 9.6)
-4.1
(-9.0, 0.3)
0.0%
Comoros44.7
(27.8, 63.0)
45.9
(28.0, 64.9)
47.9
(22.5, 74.3)
49.8
(16.3, 83.0)
-2.0
(-7.5, 3.5)
0.0%9.4
(4.2, 19.4)
11.0
(5.2, 21.7)
14.0
(5.6, 30.8)
17.7
(5.0, 46.6)
-0.2
(-5.4, 5.2)
0.0%
Congo42.8
(26.3, 60.6)
41.6
(25.3, 59.5)
40.1
(21.1, 63.0)
38.3
(15.1, 68.5)
-3.4
(-7.7, 1.0)
0.0%14.4
(7.6, 25.8)
18.4
(10.3, 30.6)
25.2
(12.8, 43.1)
33.6
(14.1, 60.9)
1.2
(-3.1, 5.9)
0.0%
Cote d`Ivoire43.9
(27.6, 61.9)
45.2
(28.5, 63.2)
47.3
(26.5, 69.0)
49.1
(22.4, 76.1)
-2.0
(-5.9, 2.2)
0.0%14.1
(7.3, 25.4)
16.6
(9.1, 27.8)
20.8
(10.6, 36.7)
25.6
(10.3, 50.2)
-0.1
(-4.7, 4.1)
0.0%
DR Congo44.7
(28.1, 62.6)
46.7
(29.6, 64.5)
49.3
(27.0, 72.1)
52.2
(21.9, 80.6)
-1.7
(-6.2, 2.9)
0.0%6.7
(3.3, 13.0)
7.4
(3.9, 13.7)
8.4
(3.8, 17.3)
9.5
(2.9, 25.8)
-1.5
(-6.4, 3.3)
0.0%
Ethiopia46.8
(30.1, 64.3)
54.9
(37.0, 71.4)
65.9
(43.7, 82.8)
75.6
(46.8, 91.4)
1.9
(-2.3, 6.3)
0.2%5.2
(2.6, 10.2)
5.5
(2.9, 10.3)
5.9
(2.7, 12.3)
6.3
(2.1, 16.7)
-2.1
(-6.4, 2.1)
0.0%
Gabon47.1
(29.7, 65.4)
54.2
(34.6, 72.3)
63.8
(36.5, 84.4)
72.8
(35.0, 93.2)
1.3
(-4.0, 7.1)
0.8%20.9
(9.9, 39.2)
28.8
(15.4, 47.3)
42.7
(21.3, 67.6)
58.0
(25.1, 86.1)
3.3
(-2.3, 9.9)
0.4%
Gambia42.5
(25.5, 60.9)
39.2
(23.9, 57.0)
34.3
(18.2, 55.5)
30.0
(12.2, 57.1)
-4.7
(-8.5, -0.6)
0.0%5.4
(2.5, 11.2)
5.9
(3.0, 11.4)
6.8
(2.9, 15.2)
7.7
(2.2, 23.2)
-1.5
(-6.5, 4.1)
0.0%
Ghana41.2
(25.2, 59.4)
39.5
(24.4, 57.3)
36.7
(18.9, 59.6)
34.3
(12.9, 65.2)
-3.8
(-8.1, 1.0)
0.0%11.4
(6.1, 20.6)
12.7
(7.2, 21.5)
14.8
(7.1, 28.3)
17.2
(6.1, 38.1)
-1.1
(-5.8, 2.8)
0.0%
Guinea44.8
(28.6, 62.6)
43.4
(27.5, 60.8)
40.9
(22.7, 62.2)
38.6
(16.7, 65.6)
-3.7
(-7.6, 0.0)
0.0%8.9
(4.5, 16.8)
10.2
(5.6, 17.8)
12.4
(6.3, 23.0)
15.0
(6.3, 32.1)
-0.7
(-4.8, 3.3)
0.0%
Kenya49.0
(31.9, 66.3)
60.9
(42.4, 76.5)
75.7
(52.9, 89.5)
86.1
(60.4, 96.2)
4.2
(-0.5, 9.7)
6.2%10.9
(5.7, 19.9)
14.6
(8.0, 25.1)
21.4
(10.3, 39.4)
30.5
(11.9, 60.4)
1.9
(-2.2, 6.9)
0.0%
Lesotho50.6
(32.6, 68.6)
64.6
(45.9, 79.2)
80.6
(60.1, 92.0)
90.5
(69.4, 97.6)
5.6
(0.4, 11.4)
17.5%22.5
(12.0, 38.3)
34.9
(21.3, 51.3)
56.4
(33.1, 77.8)
75.6
(42.3, 93.6)
6.0
(0.3, 13.2)
3.8%
Liberia46.1
(29.6, 64.0)
51.2
(32.9, 69.1)
58.5
(32.5, 80.6)
65.3
(28.8, 89.4)
0.1
(-4.9, 5.6)
0.2%8.8
(4.3, 17.1)
10.4
(5.3, 19.1)
12.8
(5.6, 26.9)
15.7
(4.9, 39.9)
-0.5
(-5.4, 4.6)
0.0%
Madagascar43.3
(27.1, 61.1)
38.1
(22.4, 57.8)
31.2
(12.9, 57.9)
25.0
(5.9, 61.6)
-5.7
(-11.2, -0.4)
0.0%3.6
(1.7, 7.2)
2.9
(1.5, 5.6)
2.2
(0.8, 5.9)
1.6
(0.3, 6.9)
-5.7
(-12.0, -0.2)
0.0%
Malawi47.5
(30.8, 65.0)
55.4
(38.0, 71.8)
66.0
(45.2, 82.1)
75.3
(49.9, 90.4)
1.7
(-2.1, 5.7)
0.1%9.2
(4.6, 17.1)
12.5
(6.8, 21.6)
18.9
(9.8, 33.6)
27.4
(11.9, 52.3)
2.0
(-1.7, 6.9)
0.0%
Mali45.1
(28.8, 62.8)
45.1
(28.4, 62.3)
45.5
(25.8, 66.8)
45.8
(20.1, 73.0)
-2.6
(-6.7, 1.4)
0.0%3.7
(1.8, 7.4)
4.1
(2.2, 7.7)
4.7
(2.2, 9.6)
5.3
(1.8, 15.5)
-1.5
(-5.8, 3.6)
0.0%
Mozambique50.6
(32.8, 68.6)
58.3
(40.2, 74.2)
68.8
(46.5, 84.5)
77.3
(48.0, 92.4)
1.7
(-3.3, 6.2)
0.4%11.4
(6.0, 20.5)
15.3
(8.6, 25.6)
22.8
(11.6, 40.4)
32.4
(14.0, 60.5)
2.0
(-1.9, 6.9)
0.0%
Namibia49.2
(31.7, 67.3)
61.6
(42.5, 77.5)
76.4
(52.0, 90.7)
86.8
(58.5, 97.0)
4.4
(-1.0, 10.4)
9.1%32.0
(17.6, 51.2)
43.4
(27.1, 61.3)
60.7
(37.0, 80.3)
75.5
(42.4, 93.2)
4.2
(-1.8, 10.8)
2.7%
Niger44.3
(27.5, 62.0)
44.8
(27.5, 63.5)
45.8
(21.4, 71.7)
46.9
(14.3, 80.7)
-2.4
(-7.8, 3.0)
0.0%2.2
(1.0, 4.6)
1.8
(0.9, 3.6)
1.4
(0.5, 3.8)
1.0
(0.2, 4.7)
-5.5
(-12.0, 0.3)
0.0%
Nigeria41.0
(24.6, 59.5)
42.2
(26.6, 60.0)
44.2
(25.4, 65.2)
46.1
(21.3, 73.6)
-2.0
(-5.9, 2.7)
0.0%8.3
(4.4, 15.1)
9.8
(5.4, 17.0)
12.2
(6.2, 22.6)
15.0
(6.2, 31.7)
-0.4
(-4.2, 3.3)
0.0%
Rwanda47.7
(30.6, 65.1)
53.8
(35.7, 71.1)
62.5
(39.0, 81.1)
70.3
(38.5, 89.6)
0.8
(-3.7, 5.3)
0.1%7.1
(3.5, 13.7)
9.7
(5.2, 17.6)
14.9
(7.0, 29.9)
22.3
(8.1, 52.3)
2.0
(-2.2, 8.2)
0.0%
Sao Tome Principe47.0
(29.9, 64.9)
52.5
(34.1, 70.4)
60.4
(35.9, 80.6)
67.7
(35.1, 89.3)
0.4
(-4.2, 5.3)
0.1%15.3
(7.5, 28.7)
20.6
(11.3, 34.3)
30.1
(15.3, 51.5)
41.8
(17.7, 72.6)
2.3
(-2.5, 8.0)
0.0%
Senegal44.9
(28.3, 62.7)
45.7
(29.7, 62.9)
46.5
(28.7, 65.4)
47.3
(25.4, 70.2)
-2.4
(-5.6, 0.9)
0.0%6.5
(3.3, 12.5)
6.9
(3.9, 12.2)
7.4
(3.9, 13.8)
7.9
(3.3, 17.9)
-2.1
(-6.0, 1.6)
0.0%
Sierra Leone43.2
(26.4, 61.6)
38.5
(23.2, 56.2)
31.9
(16.4, 52.8)
26.2
(10.0, 54.0)
-5.4
(-9.5, -1.4)
0.0%5.2
(2.6, 10.4)
5.4
(2.9, 10.2)
5.7
(2.4, 12.4)
6.0
(1.7, 18.3)
-2.3
(-7.5, 2.6)
0.0%
South Africa49.4
(31.6, 68.0)
62.4
(43.6, 78.0)
78.1
(56.6, 90.6)
88.4
(65.5, 96.8)
4.9
(0.0, 10.2)
9.6%24.2
(10.6, 46.8)
34.2
(18.7, 53.9)
51.5
(30.4, 71.9)
68.4
(38.5, 88.5)
4.3
(-0.9, 10.8)
0.5%
South Sudan45.0
(27.8, 63.3)
47.5
(27.9, 67.4)
50.7
(22.4, 78.4)
54.4
(15.9, 87.8)
-1.4
(-7.5, 4.8)
0.2%3.2
(1.4, 7.2)
3.0
(1.4, 6.6)
2.7
(0.9, 7.8)
2.4
(0.4, 10.7)
-3.9
(-10.3, 2.1)
0.0%
Swaziland51.1
(33.1, 69.3)
66.4
(48.5, 80.5)
83.2
(64.0, 93.2)
92.6
(74.5, 98.1)
6.6
(1.2, 12.5)
28.5%37.5
(21.5, 56.7)
51.7
(35.0, 67.5)
71.1
(48.9, 86.4)
85.0
(57.8, 96.1)
5.6
(-0.3, 12.4)
12.1%
Tanzania49.1
(32.0, 66.5)
57.9
(39.6, 74.2)
69.6
(45.0, 86.5)
79.4
(48.3, 94.1)
2.4
(-2.7, 7.4)
1.3%12.0
(6.5, 20.8)
13.7
(7.7, 23.0)
16.3
(8.3, 29.7)
19.5
(7.6, 40.3)
-0.7
(-5.0, 3.0)
0.0%
Togo44.1
(27.3, 62.5)
44.8
(27.8, 63.6)
45.4
(23.9, 68.8)
46.3
(18.6, 77.2)
-2.5
(-7.0, 2.1)
0.0%11.8
(5.7, 22.9)
14.4
(7.7, 25.2)
19.1
(9.3, 35.3)
24.8
(8.9, 52.2)
0.5
(-4.5, 5.6)
0.0%
Uganda49.8
(32.0, 67.9)
64.0
(45.8, 78.5)
80.5
(61.4, 91.2)
90.5
(72.2, 97.2)
5.8
(1.1, 10.8)
15.2%9.9
(5.0, 18.5)
11.8
(6.4, 20.9)
15.3
(7.5, 28.8)
19.4
(7.5, 42.1)
0.0
(-4.1, 4.4)
0.0%
Zambia48.9
(31.6, 67.1)
60.7
(42.2, 76.5)
75.4
(52.4, 89.8)
85.9
(59.5, 96.4)
4.2
(-0.9, 9.9)
6.5%15.3
(7.7, 28.4)
19.4
(10.7, 32.8)
26.8
(13.0, 47.0)
35.9
(13.6, 66.3)
1.3
(-3.6, 6.4)
0.0%
Zimbabwe47.9
(30.6, 65.5)
59.9
(42.2, 75.1)
75.0
(55.1, 88.0)
85.6
(64.7, 95.1)
4.2
(0.1, 8.9)
3.0%15.4
(8.0, 27.6)
20.4
(11.7, 32.9)
29.4
(16.3, 47.6)
40.3
(18.9, 66.4)
2.0
(-2.2, 6.8)
0.0%


Figure 1: Trends of coverage in reporting annual HIV testing and condom use from 2003 to 2030 in 38 African countries

CONCLUSIONS: We observed limited progress on TasP in Africa and little prospect of reaching global targets for HIV/AIDS elimination. Varying outcomes in countries at the same development level suggest inadequate resource allocation and low effectiveness of HIV/AIDS programs. Although some funding agencies are considering withdrawal from supporting Africa, more attention to funding and expanding testing and treatment are needed in this region.